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Vol 9, No 6 (2014) Creation of anthracycline prodrug Abstract  similar documents
A. N. Tevyashova
"... with simultaneous decrease in toxicity to normal cells. With this aim different types of anthracycline prodrugs were ..."
 
Vol 6, No 2 (2011) Lipidic strategy for improving bioavailability of nucleoside HIV reverse transcriptase inhibitor Abstract  similar documents
N. S. Shastina, E. O. Baranova, L. N. Dyakova, D. V. Lonshakov, V. I. Shvets
"... In recent years, various approaches to the prodrug design on the basis of anti-HIV active ..."
 
Vol 15, No 3 (2020) An effective method for preparation of high purity oligohexamethylene guanidine salts Abstract  PDF (Eng)  PDF (Eng)  similar documents
I. S. Ivanov, D. O. Shatalov, S. A. Kedik, I. P. Sedishev, S. V. Beliakov, K. N. Trachuk, V. V. Komarova
"... of the positive charge throughout the molecule. These polycations are then adsorbed on the cell membrane ..."
 
Vol 20, No 2 (2025) New nanostructured carriers for cellulase immobilization Abstract  PDF (Eng)  similar documents
A. M. Sulman, V. P. Molchanov, D. V. Balakshina, O. V. Grebennikova, V. G. Matveeva
"... Objectives. Cellulase is a multienzyme complex that breaks down cellulose contained in plant cell ..."
 
Vol 15, No 4 (2020) Optimization of total flavonoid content of ethanolic extract of Persicaria pulchra (Bl.) Soják for the inhibition of α-glucosidase enzyme Abstract  PDF (Eng)  PDF (Eng)  similar documents
N. H.N. Do, T. M. Le, C. D.P. Nguyen, A. C. Ha
"... -glucosidase enzyme Nga H.N. Do1,2, Tan M. Le1,2, Chinh D.P. Nguyen1,2, Anh C. Ha1,2,@ 1Faculty of Chemical ..."
 
Vol 19, No 4 (2024) Platinum(II) complexes based on derivatives of natural chlorins with pyridine-containing chelate groups as prototypes of drugs for combination therapy in oncology Abstract  PDF (Eng)  similar documents
N. S. Kirin, P. V. Ostroverkhov, M. N. Usachev, K. P. Birin, M. A. Grin
"... and are not selectively accumulated in tumor cells. If photodynamic and chemotherapy methods are combined in a single drug ..."
 
Vol 20, No 2 (2025) Production of the recombinant hemagglutinin protein of the swine influenza virus A/H1N1 and analysis of its physicochemical and antigenic properties Abstract  PDF (Eng)  similar documents
E. D. Avdonina, K. A. Pervoykina, L. V. Verkhovskaya, D. N. Shcherbinin, N. Yu. Viskova, I. S. Kruzhkova, M. A. Ilina, L. V. Kudriavtseva, L. V. Kolobukhina, M. M. Shmarov, N. A. Antipyat, A. L. Gintsburg, I. N. Tyurin
"... protein was performed by transduction of recAd5-swH1-His suspension culture of HEK293 cells in a wave-type ..."
 
Vol 15, No 2 (2020) Development and validation of a method for the determination of the specific activity of recombinant monoclonal antibody eculizumab Abstract  PDF (Eng)  similar documents
D. I. Zybin, A. S. Seregin, A. D. Askretkov, N. V. Orlova, Yu. A. Seregin, A. I. Prostyakova, D. V. Kapustin
"... of the recombinant monoclonal antibody eculizumab. Methods. The method of indirect enzyme immunoassay was used ..."
 
Vol 15, No 1 (2020) Сationic liposomes as delivery systems for nucleic acids Abstract  PDF (Eng)  similar documents
A. A. Mikheev, E. V. Shmendel, E. S. Zhestovskaya, G. V. Nazarov, M. A. Maslov
"... Objectives. Gene therapy is based on the introduction of genetic material into cells, tissues ..."
 
Vol 14, No 4 (2019) Ribavirin and its analogs: Сan you teach an old dog new tricks? Abstract  PDF (Eng)  similar documents
M. V. Chudinov
"... , respectively), which serve as substrates for many enzymes of the host cell and viruses. Viramidine 2 is also ..."
 
Vol 8, No 6 (2013) Synthesis of folate lipoconjugates with hydrophobic spacers Abstract  similar documents
E. V. Shmendel, S. V. Eremin, N. G. Morozova, M. A. Maslov
"... targeting // Adv. Enzyme Regul. 2001. V. 41. P. 189–207. 5. Xiang G., Wu J., Lu Y., Liu Z., Lee R ..."
 
Vol 11, No 6 (2016) CHANGES OF 8-OXO-2'-DEOXYGUANOSINE LEVEL IN MOUSE LIVER CELLS DNA IN CASE OF ACUTE TOXIC STRESS Abstract  PDF (Eng)  similar documents
N. V. Marmiy, D. S. Esipov
"... of 8-Oxo-2’-Deoxyguanosine Level in Mouse Liver Cells DNA in Case of Acute Toxic Stress * N ..."
 
Vol 11, No 3 (2016) The antimicrobial activity of exogeno us anionic phospholipids against Mycobacterium tuberculosis and Escherichia coli Abstract  PDF (Eng)  similar documents
Yu. L. Mikulovich, G. M. Sorokoumova, А. А. Selishcheva, V. I. Shvets
"... ), but didn’t stabilize transient complexes of the enzyme with DNA. It indicates that DNA damage due ..."
 
Vol 14, No 2 (2019) Determination of Copper(II) Ions by Diffuse Reflectance Spectroscopy Method Abstract  similar documents
I. I. Kuzmin, T. Kh. Chyong, Ya. I. Simakina, A. V. Mikhailova, Yu. I. Fabelinsky
 
Vol 15, No 2 (2020) Molybdenum(VI) oxide: New methods of synthesis and properties Abstract  PDF (Eng)  similar documents
E. E. Nikishina, E. N. Lebedeva, D. V. Drobot
"... trioxide: a) α-MoO 3 , b) β-MoO 3 , c) h-MoO 3 . In all structures, a unit cell is shown as a thin black ..."
 
Vol 5, No 2 (2010) Comparative study of enzymatic hydrolyzates of isolated soy proteins and soy flour by SE-HPLC Abstract  similar documents
E. V. Miloradova, P. A. Ivanushkin, A. A. Ananiev, S. E. Traubenberg, A. V. Sofjin
"... of proteolytic enzymes of different origin and of their multienzyme blends. ..."
 
Vol 7, No 4 (2012) Inhibitory action of exogenous cardiolipin on the bacterial type i and ii dna topoisomerases in vitro Abstract  similar documents
Yu. L. Mikulovich, G. М. Sorokoumova, А. А. Selishcheva, V. I. Shvets
 
Vol 4, No 2 (2009) Study of biochemical characteristics of products obtained by enzymatic hydrolysis of soya flour. Abstract  similar documents
E. V. Miloradova, S. E. Traubenberg, E. A. Badichko, P. A. Ivanushkin
"... the composition of amino acid products of hydrolysis of soy flour obtained by enzyme preparations Birzim P7 ..."
 
Vol 10, No 4 (2015) Neoglycoconjugates for the delivery of nucleic acids into eucaryotic cells Abstract  similar documents
M. A. Maslov, N. G. Morozova
"... acids (NA) into the target cells is one of the problem of gene therapy. Cationic liposomes are promising ..."
 
Vol 4, No 1 (2009) Features of construction of a measuring rotation devices cell for measurement viscosity Abstract  similar documents
А. А. Smirnykh
"... , измерительная ячейка, начальный период процесса. Key words: rotational viscousimetr, measuring cell, initial ..."
 
Vol 16, No 1 (2021) New-generation osteoplastic materials based on biological and synthetic matrices Abstract  PDF (Eng)  similar documents
D. D. Lykoshin, V. V. Zaitsev, M. A. Kostromina, R. S. Esipov
"... cells (MSCs) into osteoblasts and chondrocytes, which are the main cells of bone and cartilage tissue ..."
 
Vol 16, No 1 (2021) Neutron-diffraction study of the cubic-tetragonal phase structural transition in the single crystals of the solid solutions of zirconium and yttrium oxides Abstract  PDF (Eng)  similar documents
V. A. Sarin, A. A. Bush
"... was established, and the twin law for a tetragonal component (rotation of unit cell axis by 90° around the a (b ..."
 
Vol 16, No 5 (2021) Synthesis and X-ray-graphical characteristics of the MеSn2F5 (Mе = Na, K, Rb, Cs) fluoride-ion conductors Abstract  PDF (Eng)  similar documents
R. M. Zakalyukin, E. A. Levkevich, A. V. Nikolaeva
"... to KSn2F5. Based on this discovery, RbSn2F5 was reindexed to a hexagonal unit cell with parameters a = 7 ..."
 
Vol 16, No 4 (2021) Biological functions of cobalt and its toxicology and detection in anti-doping control Abstract  PDF (Eng)  similar documents
I. V. Pronina, E. S. Mochalova, Yu. A. Efimova, P. V. Postnikov
 
Vol 11, No 5 (2016) IDENTIFICATION OF EPO-Fс FUSION PROTEIN BY MEANS OF POLYACRYLAMIDE GEL-ELECTROPHORESIS WITH ISOELECTROFOCUSING (IEF-PAGE)AND IN PRESENCE OF SODIUM DODECYLSULPHATE (SDS-PAGE)/ LAUROYLSARCOSINATE (SAR-PAGE) FOR THE PURPOSE OF ANTI-DOPING CONTROL Abstract  PDF (Eng)  similar documents
P. V. Postnikov, G. I. Krotov, Yu. A. Efimova, M. A. Dikunets
"... by existing methods. During the study the enzyme for hydrolytic cleavage and optimum conditions of hydrolysis ..."
 
Vol 6, No 2 (2011) Influence of physicochemical properties of the gram-negative bacteria cell surface on the resistance to streptomycin Abstract  similar documents
A. B. Pshenichnikova, E. S. Gavrilova, V. I. Shvets
"... The surface electrokinetic and potentiometric acid-base properties of whole cells of the gram ..."
 
Vol 4, No 6 (2009) Magnetic field influence on the sedimentation of cells containing magnetic particles. Abstract  similar documents
N. N. Komova, T. A. Nikolskaya
"... . It is demonstrated that the application of magnetic field changes the speed of sedimentation of cells. Changes ..."
 
Vol 18, No 1 (2023) Method for obtaining recombinant antibodies produced by a cell line transduced with recombinant adenoviruses Abstract  PDF (Eng)  similar documents
E. S. Sedova, D. N. Shcherbinin, A. S. Bandelyuk, L. V. Verkhovskaya, N. Yu. Viskova, E. D. Avdonina, V. V. Prokofiev, E. I. Ryabova, I. B. Esmagambetov, K. A. Pervoykina, E. A. Bogacheva, A. A. Lysenko, M. M. Shmarov
"... of human HEK293 cells using transduction with recombinant adenovirus serotype 5 (rAd5) carrying genes ..."
 
Vol 15, No 5 (2020) Synthesis and biological activity of N-phosphonacetyl-L-aspartate’s structural analogs N-(α-dietoxyphosphorylcyclopropylcarbonyl)-amino acids Abstract  PDF (Eng)  similar documents
I. S. Kuzmin, G. A. Toporkov, D. Yu. Yuriev, A. V. Kalistratova, L. V. Kovalenko
"... by the enzyme aspartate transcarbamoylase (ATCase). Despite their high activity, these compounds have not found ..."
 
Vol 5, No 4 (2010) Production of hydrogen-containing gas by vapor conversion of ethanol Abstract  similar documents
M. S. Yakimova, V. F. Tretyakov, N. A. Frantsuzova, L. O. Yarygina
"... monoxide, which is necessary for further use of the obtained gas in fuel cells. ..."
 
Vol 14, No 5 (2019) Structural features of synthetic glycoconjugates and efficiency of their interaction with glycoprotein receptors on the surface of hepatocytes Abstract  PDF (Eng)  similar documents
A. S. Nosova, Yu. A. Budanova, Yu. L. Sebyakin
"... , selectively bind various glycoproteins and glycosides, facilitating their penetration into cells. This review ..."
 
Vol 19, No 3 (2024) Methylation of a group of microRNA genes as a marker for the diagnosis and prognosis of non-small cell lung cancer Abstract  PDF (Eng)  similar documents
V. I. Loginov, M. S. Gubenko, A. M. Burdennyy, I. V. Pronina, P. V. Postnikov, Yu. A. Efimova, F. V. Radus, E. S. Mochalova, T. P. Kazubskaya
"... probability of metastasis. Its most common form is non-small cell lung cancer (NSCLC). Recent studies have ..."
 
Vol 6, No 4 (2011) The system of two miscible liquids as a generator of nanoparticles. The synthesis of BaSO4 nanoparticles upon contact of precursor solutions in water and tetrahydrofuran Abstract  similar documents
E. A. Khristich, E. A. Mishchikhina, V. K. Khlebnikov, A. P. Kaplun, V. I. Popenko, Т. М. Buslaeva, L. I. Boguslavsky
"... is determined by the size of associates in the nucleation stage formed inside the rotating Bernard cells ..."
 
Vol 15, No 5 (2020) Determining the phase stability of luminescent materials based on the solid solutions of oxyorthosilicates (Lu1−xLnx)[(SiO4)0.5O0.5], where Ln = La−Yb Abstract  PDF (Eng)  PDF (Eng)  similar documents
E. I. Get’man, Yu. A. Oleksii, S. V. Radio, L. I. Ardanova
"... is calculated using the values of the substitutable structural units or dimensions of the unit cells ..."
 
Vol 17, No 5 (2022) Thiol-dependent mechanisms of selenium-containing preparations and thiolylfluanide effect on electrolytes leaching and peroxidase activity in Zea mays L. Abstract  PDF (Eng)  similar documents
P. A. Poluboyarinov, N. V. Shchetinina, I. Ya. Moiseeva, N. I. Mikulyak, N. A. Golubkina, A. P. Kaplun
"... to activate enzymes in cells of different organisms, the mechanism of enzyme activity induction is poorly ..."
 
Vol 15, No 6 (2020) Amino acid derivatives of natural chlorins as a platform for the creation of targeted photosensitizers in oncology Abstract  PDF (Eng)  similar documents
A. F. Mironov, P. V. Ostroverkhov, S. I. Tikhonov, V. A. Pogorilyy, N. S. Kirin, O. O. Chudakova, A. A. Tsygankov, M. A. Grin
"... of the glutathione antioxidant system, leading to the vulnerability of tumor cells to oxidative stress. Methods ..."
 
Vol 13, No 2 (2018) SYNTHESIS AND PROPERTIES COMPARISON OF MESO-ARYLPORPHYRINS METAL COMPLEXES AS POTENTIAL DYES FOR SOLAR CELLS Abstract  similar documents
A. V. Ezhov, F. Yu. Vyalba, K. A. Zhdanova, A. F. Mironov, K. Yu. Zhizhin, N. A. Bragina
"... solar cells (DSSC). Three different dyes were synthesized - zinc complexes of porphyrins containing ..."
 
Vol 12, No 3 (2017) LOGICAL-INFORMATION MODEL OF EVALUATION THE IMPACT OF TARGETED THERAPy DRUGS ON THE BIOLOGICAL ACTIVITy OF CANCER CELLS Abstract  similar documents
V. V. Burlyaev, А. Davydenko, V. F. Kornyushko, L. I. Russu, M. Mezentseva
"... on the life of A-549 cell cultures of the cancer origin (lung carcinoma). Preclinical studies enable ..."
 
Vol 19, No 3 (2024) Development of technology for culturing a cell line producing a single-domain antibody fused with the Fc fragment of human IgG1 Abstract  PDF (Eng)  similar documents
D. S. Polyansky, E. I. Ryabova, A. A. Derkaev, N. S. Starkov, I. S. Kashapova, D. V. Shcheblyakov, A. P. Karpov, I. B. Esmagambetov
"... ) cells stably producing GamP2C5 antibody which is a component I of the GamCoviMab candidate drug ..."
 
Vol 11, No 6 (2016) CARNOSINE-CONTAINING LIPOSOMES: PREPARATION AND PROPERTIES Abstract  PDF (Eng)  similar documents
N. A. Antonova, G. M. Sorokoumova, T. N. Fedorova, S. L. Stvolynsky, D. A. Abaimov, V. I. Popenko, V. I. Shvets
"... Carnosine is a natural dipeptide antioxidant. It is proved that it protects human’s cells from ..."
 
Vol 5, No 1 (2010) Formation of thin-film ZrO2-Y2O3 electrolyte of solid oxide fuel cell by pulsed electron-beam treatment and magnetron sputtering method Abstract  similar documents
A. A. Soloviev, N. S. Sochugov, A. V. Shipilova, V. P. Rotshtein, A. E. Tumashevskaya, K. B. Efimova
"... sputtering method for solid oxide fuel cell applications. Pulsed electron-beam treatment was used ..."
 
Vol 4, No 4 (2009) Methane route of hydrocarbons formation at very high pressure and high temperature. Abstract  similar documents
V. G. Kutcherov, A. Yu. Kolesnikov
 
Vol 16, No 2 (2021) Synthesis of ethers containing 1,3-dioxolane and gem-dichlorocyclopropane fragments Abstract  PDF (Eng)  similar documents
Sh. Sh. Dzhumaev, Yu. G. Borisova, G. Z. Raskil’dina, U. Sh. Kuzmina, R. R. Daminev, S. S. Zlotskii
"... ,3-dioxolane fragments and evaluate their cytotoxic properties against HEK293, SH-SY5Y, MCF-7, and A549 cell ..."
 
Vol 11, No 4 (2016) THE PROGNOSTIC MODEL OF ANTITUMOR EFFECT OF TARGETED DRUGS IN IMMUNOTHERAPY Abstract  PDF (Eng)  similar documents
V. V. Burlyaev, А. А. Davydenko, O. M. Nikolaeva, L. I. Russu, I. A. Suetina, M. V. Mezentseva
"... with the proliferative activity of cancer cells is proposed. The model is based on the use of inductive inference methods ..."
 
Vol 19, No 4 (2024) Erratum to the article “Development of technology for culturing a cell line producing a single-domain antibody fused with the Fc fragment of human IgG1” Abstract  PDF (Eng)  similar documents
D. S. Polyansky, E. I. Ryabova, A. A. Derkaev, N. S. Starkov, I. S. Kashapova, D. V. Shcheblyakov, A. P. Karpov, I. B. Esmagambetov
 
Vol 5, No 5 (2010) Methods of synthesis of nanoparticles and their dimensionsensitive physical parameters Abstract  similar documents
L. I. Boguslavsky
 
Vol 16, No 3 (2021) Combination of Phyllanthus amarus Schum. & Thonn. and Gymnema sylvestre R. Br. for treatment of diabetes and its long-term complications Abstract  PDF (Eng)  similar documents
T. M. Le, Ch. D.P. Nguyen, A. C. Ha
"... the α-glucosidase enzyme plays an important catalytic role in converting polysaccharides ..."
 
Vol 14, No 1 (2019) METABOLISM AND MECHANISM OF TOXICITY OF SELENIUM-CONTAINING SUPPLEMENTS USED FOR OPTIMIZING HUMAN SELENIUM STATUS Abstract  similar documents
P. A. Poluboyarinov, D. G. Elistratov, V. I. Shvets
"... deficiency. Elemental selenium penetrating through cell walls, but not through transport channels ..."
 
Vol 16, No 6 (2021) Knockdown of FLT4, Nup98, and Nup205 cellular genes as a suppressor for the viral activity of Influenza A/WSN/33 (H1N1) in A549 cell culture Abstract  PDF (Eng)  similar documents
E. A. Pashkov, E. B. Faizuloev, E. R. Korchevaya, A. A. Rtishchev, B. S. Cherepovich, А. V. Sidorov, A. V. Poddubikov, Е. P. Bystritskaya, Yu. E. Dronina, A. S. Bykov, O. А. Svitich, V. V. Zverev
"... of the influenza A virus in A549 human lung cancer cell line. Methods. The work was carried out using ..."
 
Vol 16, No 1 (2021) Comparing the original and biosimilar biotherapeutics of the monoclonal antibody eculizumab by intact mass measurement and middle-up mass spectrometry analysis Abstract  PDF (Eng)  similar documents
M. B. Degterev, R. R. Shukurov
"... of these proteoforms does not exceed 4.4%. All reported differences are expected because of using different host cell ..."
 
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