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Vol 12, No 3 (2017) LOGICAL-INFORMATION MODEL OF EVALUATION THE IMPACT OF TARGETED THERAPy DRUGS ON THE BIOLOGICAL ACTIVITy OF CANCER CELLS Abstract  similar documents
V. V. Burlyaev, А. Davydenko, V. F. Kornyushko, L. I. Russu, M. Mezentseva
"... The paper deals with laboratory preclinical studies of the impact of targeted anticancer drugs ..."
 
Vol 15, No 6 (2020) Amino acid derivatives of natural chlorins as a platform for the creation of targeted photosensitizers in oncology Abstract  PDF (Eng)  similar documents
A. F. Mironov, P. V. Ostroverkhov, S. I. Tikhonov, V. A. Pogorilyy, N. S. Kirin, O. O. Chudakova, A. A. Tsygankov, M. A. Grin
"... a and bacteriochlorophyll a for the targeted delivery of pigments to tumor foci. This will increase biocompatibility ..."
 
Vol 11, No 4 (2016) THE PROGNOSTIC MODEL OF ANTITUMOR EFFECT OF TARGETED DRUGS IN IMMUNOTHERAPY Abstract  PDF (Eng)  similar documents
V. V. Burlyaev, А. А. Davydenko, O. M. Nikolaeva, L. I. Russu, I. A. Suetina, M. V. Mezentseva
"... system of forecasting the effect of targeted anticancer drugs in immunotherapy will greatly accelerate ..."
 
Vol 8, No 2 (2013) Functional simulation of production of a new 3-rd generation photosensitizer for photodynamic therapy of cancer Abstract  similar documents
N. A. Mironova, E.V. Burlyaeva Burlyaeva
"... criteria. On the basis of functional modeling methodology there was created a complex of models in IDEF0 ..."
 
Vol 14, No 5 (2019) Structural features of synthetic glycoconjugates and efficiency of their interaction with glycoprotein receptors on the surface of hepatocytes Abstract  PDF (Eng)  similar documents
A. S. Nosova, Yu. A. Budanova, Yu. L. Sebyakin
"... which structures of synthetic carbohydrate derivatives are optimal for targeted drug delivery into liver ..."
 
Vol 9, No 4 (2014) Polyelectrolyte microcapsules modified with nanoscale titanium dioxide for targeted drug delivery Abstract  similar documents
P. А. Demina, Е. V. Degtyareva, G. M. Kuz’micheva, T. V. Bukreeva
"... MICROCAPSULES MODIFIED WITH NANOSCALE TITANIUM DIOXIDE FOR TARGETED DRUG DELIVERY P.А. Demina 1,@ , Е ..."
 
Vol 8, No 5 (2013) FUNCTIONAL SIMULATION OF PRODUCTION OF METHYL TERTIARY BUTYL ETHER Abstract  similar documents
R. Yu. Tarasenko, E. V. Burlyaeva
"... On the basis of functional modeling methodology a complex of models in IDEF0 notation was created ..."
 
Vol 13, No 5 (2018) INFORMATION-ALGORITHMIC SUPPORT FOR DEVELOPMENT OF SOLID PHARMACEUTICAL FORM Abstract  similar documents
V. F. Kornushk, I. V. Bogunova, A. A. Flid, O. M. Nikolaeva, A. A. Grebenshchikov
"... in the IDEF0 nomination. A generalized block diagram is presented that reflects, in its most general form ..."
 
Vol 15, No 2 (2020) Development and validation of a method for the determination of the specific activity of recombinant monoclonal antibody eculizumab Abstract  PDF (Eng)  similar documents
D. I. Zybin, A. S. Seregin, A. D. Askretkov, N. V. Orlova, Yu. A. Seregin, A. I. Prostyakova, D. V. Kapustin
"... pharmaceutical analysis using physicochemical, biological (in vitro), preclinical, and clinical trials. The main ..."
 
Vol 5, No 1 (2010) Design and synthesis of hydrophobic RGD-peptides derivatives Abstract  similar documents
A. V. Dobrynina, M. A. Tsykunova, Yu. L. Sebyakin
"... , направленная доставка. Key words: RGD-amino acid sequence, liposomes, targeted delivery system. Одной из ..."
 
Vol 10, No 4 (2015) Neoglycoconjugates for the delivery of nucleic acids into eucaryotic cells Abstract  similar documents
M. A. Maslov, N. G. Morozova
"... systems containing synthetic neoglycolipids are widely used for development of targeted gene delivery ..."
 
Vol 13, No 2 (2018) SYSTEM APPROACH TO INFORMATIONAL SUPPORT OF PHARMACEUTICAL DEVELOPMENT OF FINISHED MEDICINAL PRODUCTS Abstract  similar documents
V. F. Kornushko, A. V. Panov, I. V. Bogunova, O. M. Nikolayeva, A. A. Flid
"... in the IDEF0 nomination. ..."
 
Vol 15, No 5 (2020) Cationic amphiphiles based on malonic acid amides as transfection mediators Abstract  PDF (Eng)  similar documents
N. A. Romanova, U. A. Budanova, Yu. L. Sebyakin
"... Keywords: cationic lipids, malonic acid amides, cationic liposomes, transfection efficiency, targeted ..."
 
Vol 9, No 3 (2014) The development of functional-technological model of “ехtrасtum rubiae tinctоrum siccum” production Abstract  similar documents
E. Yu. Bulychev, V. V. Burlyaev, E. V. Burlyaeva, P. V. Krutov
"... representation of technological, decision making and quality test processes. The model is provided by IDEF0 ..."
 
Vol 16, No 1 (2021) Comparing the original and biosimilar biotherapeutics of the monoclonal antibody eculizumab by intact mass measurement and middle-up mass spectrometry analysis Abstract  PDF (Eng)  similar documents
M. B. Degterev, R. R. Shukurov
"... and do not affect its effectiveness and preclinical safety. Generally, the results show a high level ..."
 
Vol 19, No 4 (2024) Platinum(II) complexes based on derivatives of natural chlorins with pyridine-containing chelate groups as prototypes of drugs for combination therapy in oncology Abstract  PDF (Eng)  similar documents
N. S. Kirin, P. V. Ostroverkhov, M. N. Usachev, K. P. Birin, M. A. Grin
"... as binary agents in cancer therapy after successful preclinical trials. ..."
 
Vol 12, No 3 (2017) INFORMATIONAL AND ALGORITHMIC SUPPORT FOR DISTRIBUTION AND MARkETING LOGISTICS CONTROL SySTEMS OF PHARMACEUTICAL ENTERPRISES Abstract  similar documents
A. V. Kostrov, V. F. Kornyushko, S. Kaybullaeva, O. M. Nikolaeva
"... in the finished goods warehouse is considered. Functional models are presented in IDEF0 notation for describing ..."
 
Vol 1, No 1 (2006) Possible approach to complex liposomal drug delivery system design Abstract  similar documents
D. A. Bezrukov, T. G. Balandin, S. M. Deyev, V. V. Popenko, A. P. Kaplun
"... Problems of complex liposomal targeted drug delivery systems with controlled release ..."
 
Vol 12, No 4 (2017) FUNCTIONAL MODELING OF THE PROCESS OF CHOOSING THE BEST AVAILABLE TECHNIQUE Abstract  similar documents
K. I. Erusheva, K. Yu. Kolybanov, I. R. Tishaeva
"... was used in the graphical notation IDEF0 standardized in the Russian Federation. The production process ..."
 
Vol 9, No 3 (2014) The research applicable to elaboration of new generation of effective medicinal drugs using encapsulation of classic substances into nanocontainers Abstract  similar documents
V. I. Shvets, A. I. Lyutik
"... . These formulations are used to improve the results of treatment, to provide the targeted drug delivery ..."
 
Vol 14, No 6 (2019) Synthesis and properties of Cu- and Pd-complexes of cyclen conjugates with pheophorbide and bacteriopheophorbide Abstract  PDF (Eng)  similar documents
A. S. Smirnov, M. A. Grin, A. F. Mironov
"... ., Zheng G. Transforming a targeted porphyrin theranostic agent into a PET imaging probe for cancer ..."
 
Vol 9, No 6 (2014) Creation of anthracycline prodrug Abstract  similar documents
A. N. Tevyashova
"... . Производное PDOX (15) проходит расширен- ные доклинические испытания, в которых показано, что оно обладает ..."
 
Vol 5, No 5 (2010) The synthesis of galactose-containing amphiphiles Abstract  similar documents
Е. А. Ivanova, N. G. Morozova, М. М. Maslov, G. A. Serebrennikova
"... -tetradecylglycerol has been described. The compounds synthesized can be used as components of liposomal targeted ..."
 
Vol 4, No 6 (2009) Synthesis of the hydrocarbon components of the lipid transport systems using click-chemistry Abstract  similar documents
L. Yu. Guryeva, A. К. Bolsheborodova, Y. L. Sebyakin
"... be utilized in targeted drug delivery systems. ..."
 
Vol 14, No 4 (2019) Verification of functional models of chemical manufacturing Abstract  PDF (Eng)  similar documents
E. V. Burlyaeva, V. V. Burlyaev, V. V. Kononenko, V. S. Tsekhanovich
"... .html 2Internet source: https://www.edrawsoft.com/IDEF0-flowcharts. php Each arrow associated ..."
 
Vol 9, No 6 (2014) Liposomal systems for the delivery of biologically active compounds in the treatment of the certain diseases Abstract  similar documents
N. H. Quang, V. V. Chupin, D. I. Prokhorov, K. A. Zhdanova, V. I. Shvets
"... - фективное ингибирование роста опухолей в исследованиях in vivo. Доклинические и клинические исследо ..."
 
Vol 12, No 6 (2017) SCIENTIFIC SCHOOL OF ACADEMICIAN VITALY I. SHVETS: BIONANOPHARMACEUTICAL TECHNOLOGIES OF INNOVATIVE DIRECTED-ACTION MEDICINAL PREPARATIONS AND MANPOWER TRAINING Abstract  similar documents
V. I. Shvets, G. M. Sorokoumova, A. I. Lyutik, A. B. Pshenichnikova, D. I. Prokhorov, N. V. Rukosueva, A. G. Yakovenko, A. M. Khort, S. N. Chvalun, Yu. M. Krasnopolsky, V. Yu. Balabanyan, E. S. Severin, A. A. Kubatiev
"... , due to their gradual release. It is noted that the targeted delivery of nanoparticles makes ..."
 
Vol 16, No 3 (2021) Quality management of the chemical-technological process for continuous synthesis of pharmaceutical substances of medicinal compounds in flow microreactors Abstract  PDF (Eng)  similar documents
V. F. Kornyushko, O. M. Nikolaeva, A. V. Panov, R. R. Biglov, A. S. Kuznetsov
"... effects is laid in the development stage, and these factors are tested at the stages of preclinical ..."
 
Vol 7, No 2 (2012) Research on extractive distillation of binary heterogeneous mixtures Abstract  similar documents
V. M. Raeva, A. Yu. Sebyakin
"... . The variation of pressure can be used for targeted changes in the relative volatility of the separated ..."
 
Vol 5, No 5 (2010) System analysis of the development of grounding anodes based on conductive elastomers and used to protect metal structures from underground corrosion Abstract  similar documents
E. G. Platonova, I. J. Pashintseva, S. S. Pashintsev, V. F. Kornushko
"... основе проводов типа ПАРМ, для защиты металлических сооружений от коррозии. Рис. 1. IDEF-диаграмма ..."
 
Vol 3, No 6 (2008) The systems approach to development of integrated management system for chemical enterprises Abstract  similar documents
V. F. Kornyushko, E. G. Khomutova, E. V. Guschin
"... системы менедж- мента качества на химических промыш- ленных предприятях нами выбрана IDEF0- методология ..."
 
Vol 12, No 5 (2017) SET-THEORETIC DESCRITPION OF FUNCTIONAL MODELS OF CHEMICAL MANUFACTURING Abstract  similar documents
E. V. Burlyaeva, V. V. Burlyaev, V. S. Tsekhanovich
"... функционального модели- рования IDEF0. Методология IDEF0 обеспечивает структурированное, иерархическое, сколь ..."
 
Vol 7, No 5 (2012) The systematic aspects of the automation of environmental activities in the oil and gas companies in the Far North Abstract  similar documents
V. I. Ravicovch, M. V. Baukin, L. L. Kapitonova
"... воздействие, отходы. Рис. 2. Контекстная диаграмма функциональной модели системы ПЭМ в стандарте IDEF0 ..."
 
Vol 4, No 6 (2009) Thermodynamic and kinetic analysis of the chemical reaction of methanol dehydration to formaldehyde Abstract  similar documents
V. F. Tretyakov, A. M. Ilolov, R. M. Talyshinsky, N. A. Frantsuzova, A. S. Popov
"... stationary condition almost immediately. It is demonstrated that the induction and the targeted reaction ..."
 
Vol 4, No 2 (2009) Analysis and recommendations development for improvement of active chemical enterprise integrated management system. Abstract  similar documents
E. V. Guschin, E. G. Khomutova, V. V. Borisova
"... обработана средства- ми моделирования. Для моделирования ИСМ нами выбрана IDEF0-методология [7]. IDEF0 ..."
 
Vol 8, No 6 (2013) Synthesis of folate lipoconjugates with hydrophobic spacers Abstract  similar documents
E. V. Shmendel, S. V. Eremin, N. G. Morozova, M. A. Maslov
"... .) and gave targeted folate lipoconjugates. The structures and purity of the compounds synthesized were ..."
 
Vol 13, No 4 (2018) PHYSICO-CHEMICAL PROPERTIES OF BIODEGRADABLE HYPERBRANCHED POLYESTER POLYOL BASED ON 2,2-BIS(METHYLOL)PROPIONIC ACID Abstract  similar documents
V. I. Gomzyak, A. A. Puchkov, N. Е. Artamonova, D. K. Polyakov, G. A. Simakova, I. A. Gritskova, S. N. Chvalun
"... for targeted drug delivery. In the present study the colloidal chemical properties of the polyether polyol 2 ..."
 
Vol 18, No 4 (2023) Palladium-catalyzed allylation of norbornadiene: Experimental and quantum chemical research Abstract  PDF (Eng)  similar documents
S. A. Durakov, K. T. Egiazaryan, R. S. Shamsiev, V. R. Flid
"... , and influence technological parameters in a targeted manner. ..."
 
Vol 9, No 6 (2014) Informatization of activity eco-analysis laboratory petrochemical complex Abstract  similar documents
M. V. Bayukin, K. K. Necheukhin, V. E. Mel’nik
"... функциональной модели – методология IDEF0 (IDEF = ICAM DEFinition), рекомендованная Госстандартом [7 ..."
 
Vol 12, No 5 (2017) INTELLIGENT CONTROL SYSTEM OF CHEMICAL-TECHNOLOGICAL PROCESSES OF STRUCTURING OF MULTICOMPONENT ELASTOMER COMPOSITES BASED ON THE PRODUCTION MODEL Abstract  similar documents
A. S. Kuznetsov, V. F. Kornushko
"... , причем последняя реализована в нотации IDEF1X (рис. 6). Рис. 5. Схема управления процессами ..."
 
Vol 5, No 5 (2010) The 2-nd International symposium «Biopharma – 2010. From science to industry» Abstract  similar documents
V. I. Shvets
"... , особенности методов контроля качества и стандартизации биофармпрепаратов, особен- ности доклинической и ..."
 
Vol 14, No 3 (2019) In memory of Academician Vitaly Shvets Abstract  similar documents
"... (клинические, доклинические, биологические испытания, лабораторные исследования). Много времени Виталий ..."
 
Vol 9, No 4 (2014) The implementation of model-driven approach to software development Abstract  similar documents
O. A. Zhdanovich, A. V. Kostrov, S. V. Razlivinskaya, A. A. Timofeev
"... - цессом внедрения. Фрагмент модели процесса внедрения MDD-подхода в нотации IDEF0 представлен на рис. 1 ..."
 
Vol 12, No 1 (2017) PRINCIPLES OF CORPORATE INFORMATION SYSTEM FOR LOGISTICS MANAGEMENT OF PETROCHEMICAL ENTERPRISES Abstract  similar documents
E. A. Sobolev, A. R. Abdulgalimov, S. V. Razlivinskaya, V. F. Kornyushko
"... приведена контекстная диаграмма данной модели в нотации IDEF0. Рис. 1. Контекстная IDEF0-диаграмма ..."
 
Vol 12, No 6 (2017) TO THE QUESTION OF THE REASONS OF THE FUEL CRISIS IN THE RUSSIAN EMPIRE AT THE BEGINNING OF THE 20th CENTURY Abstract  similar documents
E. V. Bodrova, V. N. Krasivskaya
"... was due to the targeted state scientific and technical policy that was being implemented at that time ..."
 
Vol 16, No 6 (2021) Knockdown of FLT4, Nup98, and Nup205 cellular genes as a suppressor for the viral activity of Influenza A/WSN/33 (H1N1) in A549 cell culture Abstract  PDF (Eng)  similar documents
E. A. Pashkov, E. B. Faizuloev, E. R. Korchevaya, A. A. Rtishchev, B. S. Cherepovich, А. V. Sidorov, A. V. Poddubikov, Е. P. Bystritskaya, Yu. E. Dronina, A. S. Bykov, O. А. Svitich, V. V. Zverev
"... Mann–Whitney test was used. Results. In cells treated with small interfering RNAs (siRNAs) targeted ..."
 
Vol 8, No 1 (2013) Improvement of the theoretical and methodical bases of management of organizational development of chemical enterprises Abstract  similar documents
S. I. Stepnova
"... моделирования IDEF0. 10. Методы УОР необходимо применять для улучшения организации работ на уровнях (одном ..."
 
Vol 15, No 1 (2020) Сationic liposomes as delivery systems for nucleic acids Abstract  PDF (Eng)  similar documents
A. A. Mikheev, E. V. Shmendel, E. S. Zhestovskaya, G. V. Nazarov, M. A. Maslov
"... liposomes can be modified by the addition of polyethylene glycol residues or targeted ligands [18, 19 ..."
 
Vol 12, No 1 (2017) APPROACHES TO CHORIONIC GONADOTROPIN QUANTITATIVE DETERMINATION IN ANTI-DOPING CONTROL Abstract  similar documents
I. O. Zvereva, N. B. Savelieva, P. V. Postnikov, Yu. A. Efimova, M. A. Dikunets
"... ., Lovsletten K., Paus E., Halvorsen T.G., Reubsaet L. Immuno-MS based targeted proteomics: highly specific ..."
 
Vol 11, No 6 (2016) CARNOSINE-CONTAINING LIPOSOMES: PREPARATION AND PROPERTIES Abstract  PDF (Eng)  similar documents
N. A. Antonova, G. M. Sorokoumova, T. N. Fedorova, S. L. Stvolynsky, D. A. Abaimov, V. I. Popenko, V. I. Shvets
"... in the targeted drugs delivery. Мoscow: LKI Publ., 2011. 280 p. (in Russ.). 13. Maherani B., Arab-Tehrany E ..."
 
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