Production of the recombinant hemagglutinin protein of the swine influenza virus A/H1N1 and analysis of its physicochemical and antigenic properties

E. D. Avdonina; K. A. Pervoykina; L. V. Verkhovskaya; D. N. Shcherbinin; N. Yu. Viskova; I. S. Kruzhkova; M. A. Ilina; L. V. Kudriavtseva; L. V. Kolobukhina; M. M. Shmarov; N. A. Antipyat; A. L. Gintsburg; I. N. Tyurin

Fine Chemical Technologies
Tonkie Khimicheskie Tekhnologii

ISSN 2410-6593 (Print)
ISSN 2686-7575 (Online)

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Avdonina E.D., Pervoykina K.A., Verkhovskaya L.V., Shcherbinin D.N., Viskova N.Yu., Kruzhkova I.S., Ilina M.A., Kudriavtseva L.V., Kolobukhina L.V., Shmarov M.M., Antipyat N.A., Gintsburg A.L., Tyurin I.N. Production of the recombinant hemagglutinin protein of the swine influenza virus A/H1N1 and analysis of its physicochemical and antigenic properties. Fine Chemical Technologies. 2025;20(2):107-118. https://doi.org/10.32362/2410-6593-2025-20-2-107-118. EDN: QVQVOC

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ISSN 2410-6593 (Print)
ISSN 2686-7575 (Online)

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About the Authors

E. D. Avdonina
The Gamaleya National Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Russian Federation

Elena D. Avdonina, Junior Researcher, Laboratory of Molecular Biotechnology

18, Gamaleya ul., Moscow, 123098

K. A. Pervoykina
The Gamaleya National Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Russian Federation

Kristina A. Pervoykina, Junior Researcher, Laboratory of Molecular Biotechnology

Scopus Author ID 57698990900

18, Gamaleya ul., Moscow, 123098

L. V. Verkhovskaya
The Gamaleya National Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Russian Federation

Ludmila V. Verkhovskaya, Cand. Sci. (Biol.), Leading Researcher, Laboratory of Molecular Biotechnology

18, Gamaleya ul., Moscow, 123098

D. N. Shcherbinin
The Gamaleya National Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Russian Federation

Dmitriy N. Shcherbinin, Cand.Sci. (Biol.), Researcher, Laboratory of Molecular Biotechnology

Scopus Author ID 36599350900, ResearcherID E-7682-2014

18, Gamaleya ul., Moscow, 123098

N. Yu. Viskova
The Gamaleya National Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Russian Federation

Natalia Yu. Viskova, Researcher, Laboratory of Molecular Biotechnology

18, Gamaleya ul., Moscow, 123098

I. S. Kruzhkova
Infectious Disease Clinical Hospital No. 1, Moscow City Health Department; The Gamaleya National Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Russian Federation

Irina S. Kruzhkova, Infectious Disease Specialist; Researcher

63, Volokolamskoye sh., Moscow, 125367

18, Gamaleya ul., Moscow, 123098

M. A. Ilina
Infectious Disease Clinical Hospital No. 1, Moscow City Health Department
Russian Federation

Maria A. Ilina, Head of the Moscow Center for Chronic Infectious Diseases, Tick-Borne Infections, Travel Medicine and Vaccine Prevention

63, Volokolamskoye sh., Moscow, 125367

L. V. Kudriavtseva
Infectious Disease Clinical Hospital No. 1, Moscow City Health Department
Russian Federation

Larisa V. Kudriavtseva, Head of Laboratory and Diagnostic Department

63, Volokolamskoye sh., Moscow, 125367

L. V. Kolobukhina
The Gamaleya National Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation; Infectious Disease Clinical Hospital No. 1, Moscow City Health Department
Russian Federation

Lyudmila V. Kolobukhina, Dr. Sci. (Med.), Professor, Head of the Laboratory of Respiratory Viral Infections with Drug Testing; Infectious Disease Specialist, Infectious Diseases Clinical Hospital No. 1, Moscow City Health Department

Scopus Author ID 6601956811

18, Gamaleya ul., Moscow, 123098

63, Volokolamskoye sh., Moscow, 125367

M. M. Shmarov
The Gamaleya National Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Russian Federation

Maksim M. Shmarov, Dr. Sci. (Biol.), Head of the Laboratory of Molecular Biotechnology

Scopus Author ID 6507322279, ResearcherID D-8662-2014

18, Gamaleya ul., Moscow, 123098

N. A. Antipyat
Infectious Disease Clinical Hospital No. 1, Moscow City Health Department
Russian Federation

Natalya A. Antipyat, Deputy Chief Physician for Medical Affairs

Scopus Author ID 57207693166

63, Volokolamskoye sh., Moscow, 125367

A. L. Gintsburg
The Gamaleya National Center of Epidemiology and Microbiology, Ministry of Health of the Russian Federation
Russian Federation

Alexander L. Gintsburg, Full Member of the Russian Academy of Sciences, Dr. Sci. (Biol.), Professor, Director; Head of the Department of Infectology and Virology, I.M.Sechenov First Moscow State Medical University (Sechenov University)

Scopus Author ID 7005111491

18,Gamaleya ul., Moscow, 123098

8-2, Trubetskaya ul., Moscow, 119991

I. N. Tyurin
Infectious Disease Clinical Hospital No. 1, Moscow City Health Department
Russian Federation

Igor N. Tyurin, Chief Physician

Scopus Author ID 56895933300

63, Volokolamskoye sh., Moscow, 125367

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