Preview

Fine Chemical Technologies

Advanced search
Vol 1, No 1 (2006)
View or download the full issue PDF (Russian)

CHEMISTRY AND TECHNOLOGY OF MEDICINAL COMPOUNDS AND BIOLOGICALLY ACTIVE SUBSTANCES

3-4 46
Abstract
The main scientific results in the fild of natural and physiologically active substances directed to the design of new diagnostic and medical preperations are considered in the connection of 20 years from the date of establishment of the chair of biotechnology at MIFCT.
5-13 71
Abstract
Common features of nanoparticles as drug delivery venicles and some nanoformulations under development at the chair of biotechnology are considered
14-18 78
Abstract
Problems of complex liposomal targeted drug delivery systems with controlled release thermosensitive sterically stabilized active-loaded with doxorubicine and targeted with barstar liposomes producing
19-22 37
Abstract
Synthesis of purine 2'-deoxynucleoside analogues derivatives, named by using thioglycosides: 2',3'-dideoxyguanosine (3) and 2',3'-dideoxyguanosine (4) is described. This approach is based on condensation of S-glycoside (5) with silylated heterocyclic based (6,7) using N-bromosuccinimide as promoter. It is know that in the process of glycosylation reaction a mixture of three isomers, namely aN9, aN7 and bN7 is formed besides the desired bN9. In order to prevent undered formation of N7 isomers 2-aminogroup of adenine and 6-oxogroupvof guanine were modified by bulky protective gpoups
23-26 58
Abstract
A novel technique has developed to isolate recombinant human endostatin from cultured e. coli cells. endostatin was incorporated into liposomes and such liposomes were tested cytotoxic activity in vitro and for antitumor activity in vivo
27-32 58
Abstract
The opportunity of design of analogue retinal with replacement of trimethylhexenic ring of a molecule on spiropyran moiety is shown. Process of interaction of the synthesized retinal analogues with bacterioopsin from apomembrane Halobacterium salinarum and their spectral propertie of formed pigments is investigated
33-37 55
Abstract
A number of new 3'-N-alcyl and 3'-N-alkyl derivatives of 3'-amino-3'-deoxythymidine was obtained by means of nucleoside and carboxylic acids condensation. Also new 3'-N-alkyl derivatives of 3'-amino-3'-deoxythymidine was obtained by means of nucleoside alkylation with esters of a,b-unsaturated carboxylic acids
38-43 36
Abstract
The dyads composed of 2-(2-carboxyvinyl)-5,10,20-tetraphenylporphyrin and zinc complex of 5-(p-aminophenyl)-10,15,20-triphenylporphyrin were synthesized and their spectral and photophysical properties were studied
44-49 41
Abstract
Lipopeptides containing ArgGlu, OrnGlu, OrnGln, LysGlu, LysGln where synthesized. Amphiphilic properties where provided for formation of di- and monoesters L-glutamic acid and L-glutamine with various chain size of aliphatic alcohols. Parameter CCV for compounds where found and correlation between structure and behavior was determined
50-52 40
Abstract
Synthesis of meso-arylsubstituted dipyrromethanes with hydrophobic long chain groups and their application in the synthesis of trans-substituted tetraphenylporphyrins are described. The data lypoporphyrins will be investigated in the structure of modelling lipid membranes

CHEMISTRY AND TECHNOLOGY OF INORGANIC MATERIALS

53-59 54
Abstract
An improved scheme of multiple-effect evaporator is suggested. Method of calculation of units' dimensions is given. Variants of optimal energy exploitation of these evaportators were found
60-62 40
Abstract
Two polymorphic modification of nondirect anti-coagulant 2(diphenylacetyl)indandion-1,3 were studed by IR-spectroscopy. The differencies are proposed of molecular packing
63-65 38
Abstract
Method for determination of polyhexamethyleneguanidine (PG) in presence of alkyldimethylbenzylammonium (ABA) in disinfection preparations was proposed. The method based on absoption measuring of PG and eosin K ion associate at wave length 555 nm in solutions stabilized by sintanol at pH 9,2
66-70 46
Abstract
Compositions and crystallization fields of complexes in the MI2-Ur-I2-H2O (M = Mn, Co, Ni) quarternary systems were refined with the use of the data on solubility in the ternary systems including metal iodide or its urea complex, iodine and water and X-ray analysis

CHEMISTRY AND TECHNOLOGY OF ORGANIC SUBSTANCES

71-74 61
Abstract
Condensation of acetylacetone with diamines had been given products, which can be used to form complexes with salts of various metals, including the cobalt, as potential anticarcinogenic activity. The structure of acetylacetone with 1,6-hexamethylenediamine has been studied by X-ray


ISSN 2410-6593 (Print)
ISSN 2686-7575 (Online)