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Тонкие химические технологии

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ОПРЕДЕЛЕНИЕ ФЕНОЛЬНЫХ СОЕДИНЕНИЙ В ДЕЗИНФЕКЦИОННЫХ СРЕДСТВАХ

https://doi.org/10.32362/2410-6593-2017-12-3-5-20

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Аннотация

Рассмотрены аспекты аналитического определения дезинфектантов производных ряда фенола. Показана возможность совместного определения пяти производных данного ряда в различных дезинфицирующих средствах с использованием ОФ ВЭЖХ в изократическом режиме (УФ-детектирование). Альтернативно рассмотрены возможности определения с использованием методов спектрофотометрии и ГЖХ. Настоящее и предшествующие исследования показали, что экстракционное извлечение производных группы фенола органическими растворителями из широкого спектра дезинфицирующих средств доступно только в некоторых случаях, преимущественно при использованием гексана в качестве экстрагента. В дальнейшем спектрофотометрирование гексановых экстрактов не всегда позволяет корректно скомпенсировать влияние фоновых примесей и требует дополнительного разделения компонентов. Исходя из литературных данных и результатов экспериментов, стоит отметить, что производительнее осуществлять анализ всей линейки дезинфекционных препаратов в изопропаноле (иногда в воде) хроматографическими методами, отдавая предпочтение ВЭЖХ. При этом пробоподготовка сводится к солюбилизации навесок готовых средств в изопропаноле/воде. Хроматографическое исследование оптимально проводить с применением в качестве элюента систем на основе ацетонитрила, обеспечивающих корректное определение (λ = 280 нм) производных фенола.

Об авторах

А. А. Носикова
Московский технологический университет (Институт тонких химических технологий)
Россия

кандидат химических наук, доцент кафедры химии и технологии редких и рассеянных элементов, наноразмерных и композиционных материалов им. К.А. Большакова И

119571, Россия, Москва, пр-т Вернадского, д. 86



И. О. Мельников
Институт общей и неорганической химии им. Н.С. Курнакова РАН
Россия

кандидат химических наук, заведующий сектором прикладной экологии воды

119991, Россия, Ленинский пр-т, д. 31



А. Н. Кочетов
АО «БВТ БАРЬЕР РУС»
Россия

кандидат химических наук, химик-аналитик испытательной аналитической лаборатории А

143900, Россия, Московая область, Балашиха, ул. Парковая, д. 3



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Для цитирования:


Носикова А.А., Мельников И.О., Кочетов А.Н. ОПРЕДЕЛЕНИЕ ФЕНОЛЬНЫХ СОЕДИНЕНИЙ В ДЕЗИНФЕКЦИОННЫХ СРЕДСТВАХ. Тонкие химические технологии. 2017;12(3):5-20. https://doi.org/10.32362/2410-6593-2017-12-3-5-20

For citation:


Nosikova L.A., Melnikov I.O., Kochetov A.N. THE DETERMINATION OF PHENOLS COMPOUNDS IN DISINFECTANTS. Fine Chemical Technologies. 2017;12(3):5-20. (In Russ.) https://doi.org/10.32362/2410-6593-2017-12-3-5-20

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