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ESTABLISHMENT OF ISOMERIC COMPOSITION OF INSECTICIDAL CYPERMETHRIN SUBSTANCE BY RP-HPLC

https://doi.org/10.32362/2410-6593-2017-12-1-76-82

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Abstract

The determination of cypermethrin, one of the most sought pyrethroid insecticides having a wide range of activities, by isocratic RP-HPLC is considered. The analysis of substances (technical products) with different content of both the geometrical (cis-, trans-) and optical (zetacypermethrin and alfacypermethrin) isomers of cypermethrin was carried out. Information about the content of the most active forms of cis- allows evaluating the effectiveness of the biological substance based only on RP-HPLC data, which in turn can be a decisive factor in the of the substance assessment supplier / manufacturer or ready commercial products. The optimum concentration range for determining the geometric isomers of cypermethrin in the working solution is from 0.2 to 1.0 mg/ml. The substance detection limit in working solutions/washings is 0.005 mg/ml.

About the Authors

L. A. Nosikova
Moscow Technological University (Institute of Fine Chemical Technologies)
Russian Federation
Moscow,119571 Russia


A. N. Kochetov
CJCS «METTEM-Technology»
Russian Federation
Balashikha, Moscow region, 143900 Russia


References

1. Кostina M.N., Malʼtseva M.N., Novikova E.A., Lopatina Yu.V. The prospects for the creation of forms for professional treatments based on new registered substances // Dezinfektsionnoe delo (Disinfection Affairs). 2005. № 3. P. 44–47. (in Russ.).

2. Makhneva T.V., Chepko V.I., Zakharchenko A.V. [et al.] The contribution of domestic producers of means of disinfection, disinsection and deratization in the development of disinfection business in the Russian Federation // Dezinfektsionnoe delo (Disinfection Affairs). 2006. № 3. P. 17–22. (in Russ.).

3. Zakladnoy G.A. Battle for grain: we or insects? // Zaschita i karantin rastenij (Plant Protection and Quarantine). 2011. № 1. P. 47–51. (in Russ.).

4. Naumann K. Chemistry of plant protection. Heidelberg: Springer-Verlag. V. 4: Synthetic pyrethroid insecticides: structure and properties, 1990. 241 p.

5. Levi M.I., Gorokhova T.S., Beklemesheva L.N. The simplified method of determining the sensitivity of red cockroaches of wild populations to various insecticides // Dezinfektsionnoe delo (Disinfection Affairs). 1992. № 1. P. 26–33. (in Russ.).

6. Roslavtseva S.A., Eremina O.Yu., Bakanova E.I. [et al.] Sensitivity of laboratory race of red cockroaches Blatella germanica (L.) to insecticides // Dezinfektsionnoe delo (Disinfection Affairs). 2005. № 3. P. 58–62. (in Russ.).

7. Eremina O.Yu., Olifer V.V., Roslavtseva S.A., Bendrycheva S.N. The study of resistance of red cockroaches to insecticides from different classes by topical method // Dezinfektsionnoe delo (Disinfection Affairs). 2015. № 3. P. 40–45. (in Russ.).

8. R 4.2.2643-10. Methods of laboratory research and testing of disinfectants to assess their efficacy and safety. Federal’nyj centr gigieny i ehpidemiologii Rospotrebnadzora (Federal Сenter of Hygiene and Epidemiology of Rospotrebnadzor) . Moscow, 2010. 615 p. (in Russ.).

9. Amelin V.G., Bolʼshakov D.S., Tretʼyakov A.V. Identification and determination of synthetic pyrethroids, chlorpyrifos and neonicotinoids in water by gas and liquid chromatography // Journal of Analytical Chemistry (Rus). 2012. V. 67. № 4. P. 386–391. (in Russ.).

10. Naobumi Ô., Hajimu K., Reiko K. // J. Chromatogr. 1990. V. 515. Р. 441–450.

11. Yu Y. // J. Chin. Mass Spectrom. Soc. 2000. V. 21. № 3-4. Р. 23–24.

12. Nosikova L.A., Kochetov A.N. Determination of lambda-cyhalothrine in microincapsulated insecticidal compositions // Tonkie khimicheskie tekhnologii (Fine Chemical Technologies). 2016. V. 11. № 1. P. 88–95. (in Russ.).

13. Nosikova L.A., Kochetov A.N. The possibilities of establishing the isomeric composition of active substances in insecticidal compositions // Dezinfektsionnoe delo (Disinfection Affairs). 2016. № 1. P. 45–57. (in Russ.).

14. Kochetov A.N., Shestakov K.A., Shpilevskij G.M., Kuz'mina L.G. Determination of the content of 4-hydroxycoumarins substituted in the third position in the disinfection tools and pharmaceuticals // KhimikoFarmatsevticheskii Zhurnal (Chemical-Pharmaceutical Journal). 2013. V. 47. № 2. P. 41–50. (in Russ.).

15. Shestakov K.A., Kochetov A.N., Voychishina D.V. Modern microencapsulated insecticidal agents "Microcyn+" and "Microfos+": main features and application experience // Dezinfektsionnoe delo (Disinfection Affairs). 2009. № 2. P. 58–59. (in Russ.).

16. Muntiyan E.M., Batko M.G., Yazlovetskiy I.G. The sensitivity to insecticides of western flower thrips (Frankliniella occidentalis (Pergande)) (Thysanoptera: Thripidae)// Agrochimiya (Аgricultural Chemistry). 2014. № 2. P. 33–38. (in Russ.).

17. Sokolyanskaya M.P. Formation of resistance to pyrethroids in larvae of the housefly Musca domestica // Agrochimiya (Аgricultural Chemistry). 2014. № 3. P. 54–59. (in Russ.).

18. Vishnyakova I.I., Guzalova A.G., Sidorova L.A. Application of the biotesting method to assess the toxicity of pesticides // Veterinarnyj vrach (Veterinarian). 2015. № 5. P. 9–13. (in Russ.).


For citation:


Nosikova L.A., Kochetov A.N. ESTABLISHMENT OF ISOMERIC COMPOSITION OF INSECTICIDAL CYPERMETHRIN SUBSTANCE BY RP-HPLC. Fine Chemical Technologies. 2017;12(1):76-82. (In Russ.) https://doi.org/10.32362/2410-6593-2017-12-1-76-82

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ISSN 2410-6593 (Print)
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