8-оксо-2’-дезоксигуанозин - биомаркер окислительного стресса

8-Оксо-2’-дезоксигуанозин (8-oxo-dG) является преобладающей формой свободнорадикального повреждения ДНК. C момента его обнаружения в 1983 году, это соединение определяют в различных тканях и жидкостях организма: в крови, моче, мозге, печени и др. В данном обзоре рассматривается роль 8-oxo-dG в качестве биомаркера окислительного стресса, предиктора течения заболевания и успеха применяемой терапии у больных, а также методы, с помощью которых он сегодня детектируется в биологических образцах.

8-оксо-2'-дезоксигуанозин, окислительный стресс, биомаркеры окислительного стресса

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