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COMPLEXES OF SILVER, LEAD, CALCIUM WITH BISPHOSPHONIC LIGANDS

https://doi.org/10.32362/2410-6593-2018-13-5-23-29

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Abstract

It is interesting in chemical terms and promising in the applied production of new complexes of metals with bisphosphonic ligands with a popular set of consumer properties. To date, little has been studied chemistry of bisphosphonic acid complexes with the basic structure of 1-hydroxymethylene-bisphosphonic acid with a side chain containing 11 carbon atoms and ending with an amino group. The main objective is to obtain new bisphosphonates of s-, p -, d - and f-elements, their characterization by a complex of physical and chemical research methods (NMR and IR spectrometry, RSA, DTA, optical microscopy, laser diffraction) and to identify new applications of bisphosphonic acids and their salts. In the course of the work, complexes of Ag, Pb, Ca, with 1-hydroxymethylene-bisphosphonic acid (H2N(CH2)xC(OH)(H2PO3)2) and its derivatives, the side chain ends with an amino group, its length is 11 carbon atoms. Crystal structures of metal-bisphosphonate complexes with the general formula H2N(CH2)10C(OH)(HPO3)xM (M = Ag, Pb, Ca) were determined. The complexes were characterized by IR spectroscopy and 31P solid-state NMR spectroscopy, RSA. The areas of practical use of the complexes are outlined. It is shown, by the example of wastewater in Kuopio, Finland, that bisphosphonic acids can be used for wastewater treatment of enterprises from heavy metals (M =Pb, Zn, Cd, etc.).

About the Authors

A. V. Galantsev
MIREA - Russian Technological University (M.V. Lomonosov Institute of Fine Chemical Technologies); LLC "Skybiochem"
Russian Federation

Postgraduate Student, K.A. Bolshakov Chair of Chemistry and Technology of Rare and Scattered Elements, Nanoscale and Composite Materials

86, Vernadskogo Pr., Moscow, 119571, Russia

Deputy General Director

2, Mayakovsky St., microdistrict Yubileiny, Korolev, Moscow region, 141090, Russia



M. Haukka
University of Eastern Finland (UEF)
Finland

Professor

7, Yliopistokatu, Joensuu, 80130, Finland



D. V. Drobot
MIREA - Russian Technological University (M.V. Lomonosov Institute of Fine Chemical Technologies)
Russian Federation

D.Sc. (Chemistry), Professor, K.A. Bolshakov Chair of Chemistry and Technology of Rare and Dispersed Elements, Nanoscale and Composite Materials

86, Vernadskogo Pr., Moscow 119571, Russia



References

1. Menschutkin M. Ueber die Einwirkung des Chloracetyls auf phosphorige Saure. Ann. Chem. Pharm. 1865; 133: 317-320.

2. Fleisch H., Russell R.G.G., Bisaz S., Casey P.A., Mühlbauer R.C. The influence of pyrophosphate analogues (diphosphonates) on the precipitation and dissolution of calcium phosphate in vitro and in vivo. Calcif. Tissue Res. 1968; 2:(Suppl): 10-10A.

3. Fleisch H.A., Neuman W.E. Mechanisms of calczjication: Role of collagen, polyphosphates, and phosphatase. Am. J. Physiol. 1961; 200: 1296-1300.

4. Fleisch H.A., Bisaz S. Isolation from urine of pyrophosphate-α calcification inhibition. Am. J. Physiol. 1962; 203: 671-675.

5. Jayswal A., Chudasama U. Synthesis and characterization of a new phase of zirconium phosphate for the separation of metal ions. J. Iran. Chem. Soc. 2007; 4(4): 510-515.

6. Mao G.Q., Guillou N., Nogues M., Cheetham A.K., Ferey G. Structure and magnetism of VSB-2, -3, and -4 or Ni4(O3P-(CH2)-PO3)2·(H2O)n (n = 3, 2, 0), the first ferromagnetic nickel(II) diphosphonates: Increase of dimensionality and multiple coordination changes during a quasi topotactic dehydration. Chem. Mater. 1999; 11: 2937-2947.

7. Sun Z.M., Prosvirin A.V., Zhao H.H., Mao J.G., Dunbar K.R. New type of single chain magnet based on spin canting in an antiferromagnetically coupled Co(II) chain. J. Appl. Phys. 2005; 97: 10B305.

8. Bourelly S., Liewellyn P.L., Serre C., Millanger F., Loiseau Th., Ferey G. Different adsorption behaviors of methane and carbon dioxide in the isotypic nanoporous metal terephthalates MIL-53 and MIL-47. J. Am. Chem. Soc. 2005; 127: 13519-13521.

9. Serre C., Ferey G. Hydrothermal synthesis, structure determination from powder data of a threedimensional zirconium diphosphonate with an exceptionally high thermal stability: Zr(O3P-(CH2)-PO3) or MIL-57. J. Mater. Chem. 2002; 12(8): 2367-2369.

10. Zhang Z.C., Gao S., Zheng L.M. Cobalt diphosphonate with a new double chain structure exhibiting field-induced magnetic transition. Dalton Trans. 2007; 4681-4684.

11. Beutner R., Michael J., Schwenzer B., Scharnweber D. Biological nano-functionalization of titanium-based biomaterial surfaces: A flexible toolbox. JRS Interface. 2010; 7: 93-105.

12. Benabdellah M., Dafali A., Hammouti B., Aouniti A., Rhomari M., Raada A., Senhaji O., Robin J. The role of phosphonate derivatives on the corrosion inhibition of steel in HCl media. Chem. Eng. Commun. 2007; 194: 1328-1341.

13. Tylor J.M., Mahmoudkhani A.H., Shimizu G.K.H. A tetrahedral organophosphonate as a linker for a microporous copper framework. Angew. Chem. Int. Ed. Engl. 2007; 46: 795-798.

14. Mukherjee S., Huang C., Guerra F., Wang K., Oldfield E. Thermodynamics of bisphosphonates binding to human bone: A two-site model. J. Am. Chem. Soc. 2009; 131: 8374-8375.


For citation:


Galantsev A.V., Haukka M., Drobot D.V. COMPLEXES OF SILVER, LEAD, CALCIUM WITH BISPHOSPHONIC LIGANDS. Fine Chemical Technologies. 2018;13(5):23-29. https://doi.org/10.32362/2410-6593-2018-13-5-23-29

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ISSN 2410-6593 (Print)
ISSN 2686-7575 (Online)