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PHYTOPREPARATIONS IN THE PREVENTION AND TREATMENT OF URATE NEPHROLITHIASIS

https://doi.org/10.32362/2410-6593-2017-12-6-39-45

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Abstract

The composition, structure and specific features of urate calculi are discussed in the article. It was shown that they consist of 95% of uric acid and its salts on an average by the X-ray phase and energy dispersive analysis of a number of samples extracted from the urinary tract of 24 urological patients. The mechanism of formation of urate stones is considered. It is noted that urate stones are formed at a urine under pH below 5.5. The factors reducing the development of urinary urolythiasis and uraturia are indicated. The drugs commonly used for the treatment and prevention of urate nephrolithiasis are listed. The role of phytotherapy is underlined in the treatment of urolithiasis in general and urate nephrolithiasis in particular. It is concluded that the composition of plant compositions should include natural compounds of the alkaloid class. The most promising compositions of medicinal plants were determined, and the effect of herbal extracts of various compositions on the pH of the solution and the loss of stone mass

About the Authors

N. G. Chaban
Moscow Technological University (M.V. Lomonosov Institute of Fine Chemical Technologies)
Russian Federation

Ph.D. (Chemistry), Associate Professor of the Chair of General Chemical Technology

86, Vernadskogo Pr., Moscow 119571, Russia



A. Yu. Putin
Moscow Technological University (M.V. Lomonosov Institute of Fine Chemical Technologies)
Russian Federation

Ph.D. (Chemistry), Assistant Professor of the Chair of General Chemical Technology

86, Vernadskogo Pr., Moscow 119571, Russia



L. M. Rapoport
I.M. Sechenov First Moscow State Medical University, Scientific Research Institute of Uronephrology and Human Reproductive Development
Russian Federation

Dr.Sc. (Medicine), Professor, Deputy Director of the Scientific Research Institute of Uronephrology and Human Reproductive Development

2, Bld. 1, Bol’shaya Pirogovskaya st., Moscow 119435, Russia)



T. M. Buslaeva
Moscow Technological University (M.V. Lomonosov Institute of Fine Chemical Technologies)
Russian Federation

Dr.Sc. (Chemistry), Professor of the K.A. Bolshakov Chair of Chemistry and Technology of Rare and Scattered Elements, Nanoscale and Composite Materials

86, Vernadskogo Pr., Moscow 119571, Russia



References

1. Borisov V.V., Dzeranov N.K. Urolithiasis. Therapy of patients with kidney stones and ureters. Мoscow: Rossiyskoe obshchestvo urologov (Russian Society of Urologists), 2011. 88 p. (in Russ.).

2. Apolikhin O.I. Status of providing urological assistance in Russia and the task of the service for the implementation of the national project "Health". Ways to improve the education of a urologist. 9 Vserossiyskiy s’ezd urologov (The 9th All-Russian Congress of Urology): abstracts. Мoscow, 2007. P. 3−32. (in Russ.).

3. Liebman S.E., Taylor J.G., Bushinsky D.A. Uric acid nephrolithiasis // Curr. Rheumatol. Rep. 2007. V. 9. P. 251–257.

4. Dombrovskiy Ya.A. Drug treatment of urolithiasis of patients with citrate therapy // Zhurnal «Pochki» (The journal "Kidneys"). 2014. V. 1. № 7. P. 45–52. (in Russ.).

5. Cherepanova E.V., Dzeranov N.K. Metaphylaxis of urolithiasis on an outpatient basis // Experimental’naya i klinicheskaya urologiya (Experimental and Сlinical Urology). 2010. № 3. P. 33–39. (in Russ.).

6. Ivanov V.I. Herbal medicine. The newest directory. Мoscow: Eksmo Publ., 2006. 544 p. (in Russ.).

7. Levkovskiy S.N., Protoshchak V.V., Dzhalilov I.B. Effect of Blamaren on urine saturation with urate stone-forming compounds // Terra Medica. Urologiya (Terra Medica. Urology). 2010. № 4. P. 31–35. (in Russ.).

8. Kukes V.G. Phytotherapy with the basics of clinical pharmacology. Мoscow: Meditsina Publ., 1999. 192 p. (in Russ.).

9. Levkovskiy S.N. Urolithiasis: Flow forecasting and metaphylaxis. St. Petersburg: Tipografiya Beresta Publ., 2010. 120 p. (in Russ.).

10. Aggarval A., Singla S.K, Tandon C. Urolithiasis: Phytotherapy as an adjunct therapy // Ind. J. Exp. Biol. 2014. V. 53. P. 103–111.

11. Miroshnikov V.M. Medicinal plants and herbal preparations in urology. Мoscow: MEDpress Publ., 2005. 240 p. (in Russ.).

12. Pshukova I.V., Konovalov D.A., Karpenko V.A., Ligay L.V., Kuleshova S.A. Phytochemical and pharmacological study of annual sunflower roots // Khimiya rastitel'nogo syr'ya (Chemistry of Plant Raw Materials). 2014. № 2. P. 189–194. (in Russ.).

13. Murav’yova D.A. Pharmacognosy. Мoscow: Meditsina Publ., 1991. 560 p. (in Russ.).

14. Pytel’ Yu.A., Zolotarev I.I. Urinary nephrolithiasis. Мoscow: Meditsina Publ., 1995. 176 p. (in Russ.).

15. Sinyakov A.F. Medicinal Herbs. Мoscow: Eksmo Publ., 2010. 608 p. (in Russ.).

16. Tiktinskiy O.L., Aleksandrov V.P. Urolithiasis. Series: "Modern Medicine". St. Petersburg: Piter Publ., 2000. 384 p. (in Russ.).

17. Chaban N.G., Rapoport L.M., Tsarichenko A.A., Buslaeva Т.М. Phytopreparations for the treatment and prevention of phosphate nephrolithiasis // Tonkiye khimicheskiye tekhnologii (Fine Chemical Technologies). 2015. V. 10. № 3. P. 62–69. (in Russ.).


For citation:


Chaban N.G., Putin A.Yu., Rapoport L.M., Buslaeva T.M. PHYTOPREPARATIONS IN THE PREVENTION AND TREATMENT OF URATE NEPHROLITHIASIS. Fine Chemical Technologies. 2017;12(6):39-45. (In Russ.) https://doi.org/10.32362/2410-6593-2017-12-6-39-45

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ISSN 2410-6593 (Print)
ISSN 2686-7575 (Online)