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The preparation of 1-(β-naphthyl)-3-ferrocenylpyrazole-4-carbaldehyde and syntheses on the base of it

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Abstract

Synthesis of 1-(β-naphthyl)-3-ferrocenyl pyrazole-4-carbaldehyde was carried out from acetylferrocene and naphthalen-2-ylhydrazine followed by intramolecular cyclization under Vilsmeier-Haack conditions. The reaction of reductive amination of aldehydes obtained with primary and secondary amines including methyl esters of amino acids was studied.

About the Authors

E. Yu. Osipova
МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86
Russian Federation


A. A. Simenel
Институт элементоорганических соединений им. А.Н. Несмеянова РАН
Russian Federation


A. N. Rodionov
Институт элементоорганических соединений им. А.Н. Несмеянова РАН
Russian Federation


V. V. Kachala
Институт органической химии им. Н.Д. Зелинского РАН
Russian Federation


K. Ya. Zherebker
МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86
Russian Federation


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For citation:


Osipova E.Yu., Simenel A.A., Rodionov A.N., Kachala V.V., Zherebker K.Y. The preparation of 1-(β-naphthyl)-3-ferrocenylpyrazole-4-carbaldehyde and syntheses on the base of it. Fine Chemical Technologies. 2009;4(2):100-105. (In Russ.)

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