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Investigation and optimization of drug encapsulation by fluid-bed coating

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Abstract

The drug encapsulation by enteric film fluid-bed coating has been investigated. Influence of each operation parameter on product quality has been estimated and optimal conditions included film thickness have been determined. The model drug release kinetics of encapsulation product has been studied.

About the Authors

M. G. Gordienko
Российский химико-технологический университет им. Д.И. Менделеева
Russian Federation


Ju. V. Makovskaya
Российский химико-технологический университет им. Д.И. Менделеева
Russian Federation


A. O. Kasimova
Российский химико-технологический университет им. Д.И. Менделеева
Russian Federation


N. V. Menshutina
Российский химико-технологический университет им. Д.И. Менделеева
Russian Federation


References

1. Солодовник, В. Д. Микроинкапсулирование / В. Д. Солодовник. - М. : Химия, 1980. -216 с.

2. Air-suspension particle coating in the food industry: Part I - state of the art / R.L. Stephen [et al.] // Powder Technology. - 2007. - № 171. - P. 25-33.

3. Air-suspension particle coating in the food industry: Part I - micro-level process approach / R. L. Stephen [et al.] // Powder Technology. - 2007. - № 171. - P. 34-45.

4. Ахназарова, С. Л. Методы оптимизации эксперимента в химической технологии : Учеб. пособие для хим.-технол. спец. вузов. - 2-е изд., перераб. и доп. / С. Л. Ахназарова, В. В. Кафаров. - М. : Высшая школа, 1985. - 327 с.


For citation:


Gordienko M.G., Makovskaya J.V., Kasimova A.O., Menshutina N.V. Investigation and optimization of drug encapsulation by fluid-bed coating. Fine Chemical Technologies. 2010;5(1):93-97. (In Russ.)

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ISSN 2410-6593 (Print)
ISSN 2686-7575 (Online)