Synthesis and study of cytotoxic and hemolytic activity of cationic glycerolipids alkyl type. Synthesis and study of cytotoxic and hemolytic activity of cationic glycerolipids alkyl type.
Abstract
About the Authors
S. G. RomanovaRussian Federation
G. A. Serebrennikova
Russian Federation
A. A. Shtil
Russian Federation
References
1. Gajate, C. Biological activities, mechanisms of action and biomedical prospects of the antitumor ether phospholipid ET-18-OCH3 (Edelfosine), a proapoptotic agent in tumor cells / C. Gajate, F. Mollinedo // Curr. Drug Metab. – 2002. – Vol.3. – P. 491–525.
2. Selective induction of apoptosis in cancer cells by the ether lipid ET-18-OCH3 (Edelfosine):molecular structure requirements, cellular uptake, and protection by Bcl-2 and Bcl-X(L) / F. Mollinedo, J.L. Fernandez-Luna, C. Gajate, B. Martin-Martin, A. Benito, R. Martinez-Dalmau, M. Modolell // Cancer Res. – 1997. – Vol. 57. – P. 1320–1328.
3. Mollinedo, F. Early and selective induction of apoptosis in human leukemic cells by the alkyllysophospholipid ET-18-OCH3 / F. Mollinedo, R. Martinez-Dalmau, M. Modolell // Biochem. Biophys. Res. Commun. – 1993. – Vol. 192. – P. 603–609.
4. Civoli, F. Differentiation of HL-60 cells distinguishes between cytostatic and cytotoxic effects of the alkylphospholipid ET-18-OCH3 / F. Civoli, S. B. Pauig, L. W. Daniel // Cancer Chemother. Pharmacol. – 1996. – Vol. 38. – P. 269–273.
5. Berdel, W. E. Synthetic alkyl-phospholipid analogs: a new class of antitumor agents / in Phospholipids and Cellular Regulation / W. E. Berdel, R. Andereesen, P. G. Murder. – Plenum Publishing Corporation, 1989. – P. 42–73.
6. Novel membrane-interactive ether lipid analogs that inhibit infectious HIV-1 production and induce defective virus formation / L. S. Kucera, N. Iyer, E. Leake, A. Raben, E. J. Modest, L. W. Daniel, C. Piantadosi // AIDS Res. Hum. Retroviruses. – 1990. – Vol. 6, № 4. – P. 491–496.
7. Синтез бесфосфорных пиридинсодержащих глицеролипидов с простой эфирной связью / С. Г. Романова, В. Г. Романов, Н. В. Плявник, Г. А. Серебренникова, А. А. Штиль / Вестник МИТХТ. – 2008. – Вып. 3, № 4. – С.53–57.
8. Mossman, T. Rapid colorimetric assay for cellular growth and survival: application to proliferation / T. Mossman // J. Immunol. Methods. – 1983. – Vol. 89. – P. 271–277.
9. Ермохин, В. А. Синтез и гемолитическая активность N-адамантоилзамещённых гетероциклических аминов и анилинов / В. А. Ермохин, П. П. Пурыгин, Н. А. Кленова // Вестник СамГУ. – 2004. – Вып. 4, № 34. – С. 138–144.
Review
For citations:
Romanova S.G., Serebrennikova G.A., Shtil A.A. Synthesis and study of cytotoxic and hemolytic activity of cationic glycerolipids alkyl type. Synthesis and study of cytotoxic and hemolytic activity of cationic glycerolipids alkyl type. Fine Chemical Technologies. 2008;3(5):104-108. (In Russ.)