Solid-phase synthesis of negatively charged pna decamer with GlyψL-Glu pseudopeptide bond.
Abstract
Solid-phase Boc-protocol and synthetic strategy of negatively charged peptide nucleic acids has been suggested. New thymine containing negatively charged PNA decamer based on L-glutamic acid and glycine was synthesized.
About the Authors
N. P. Boyarskaya
M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571
Russian Federation
Russian Federation
Yu. G. Kirillova
M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571
Russian Federation
Russian Federation
D. S. Esipov
МГУ им. М.В. Ломоносова
Russian Federation
Russian Federation
V. I. Shvets
M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571
Russian Federation
Russian Federation
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Review
For citations:
Boyarskaya N.P., Kirillova Yu.G., Esipov D.S., Shvets V.I. Solid-phase synthesis of negatively charged pna decamer with GlyψL-Glu pseudopeptide bond. Fine Chemical Technologies. 2007;2(5):33-36. (In Russ.)
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