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THE DEVELOPMENT OF A BASIC PROCESS SCHEME FOR THE PREPARATION OF ISOAMYL ACETATE

https://doi.org/10.32362/2410-6593-2018-13-6-79-88

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Abstract

The article reports the development of a technological scheme for isoamyl acetate preparation on the basis of kinetic data, vapor-liquid and liquid-liquid equilibrium data. A review of isoamyl acetate production methods was made. At present most of the methods are based on esterification reaction, which takes place in the presence of homogenous and heterogeneous catalysts. Heterogeneous catalysis is preferred because of absence the catalyst separation problem. In the first part of the work vapor-liquid and liquid-liquid equilibrium simulation was made. NRTL and UNIQUAC models were used to calculate phase equilibrium of a quaternary reaction mixture. It was proved by comparison of deviations of the calculated temperature and vapor mole fractions from the experimental values that NRTL is the best model for the considered mixture phase equilibrium calculations. This model was used in further calculations of distillation and liquid-liquid splitting. The choice of the technological scheme is based on the use of the principle of both distillation and liquid phase separation and the recycling of substances in the system. The difficulty in isolating pure isoamyl acetate as a product is due to the presence of four binary azeotropes and two triple ones in the system. When developing and selecting a technological scheme, the possibility of obtaining maximum conversions of the reactants was taken into account. Besides, when designing and calculating the scheme, an assumption was made about infinite separating ability of separation distillation columns. To check operating efficiency of the scheme in real conditions, a verification calculation was made to determine the minimum and working reactor volume. The minimum and working reactor volume calculation was based on the Langmuir-Hinshelwood-Hougen-Watson model for the kinetics of the esterification reaction. The selection of constructive and operating parameters of the scheme, at which high quality of isoamyl acetate is achieved, was made.

About the Authors

S. L. Nazanskiy
MIREA - Russian Technological University (M.V. Lomonosov Institute of Fine Chemical Technologies)
Russian Federation

Ph.D. (Engineering), Associate Professor of the Chair of Chemistry and Technology of Basic Organic Synthesis

86, Vernadskogo pr., Moscow 119571, Russia



M. S. Glukhova
MIREA - Russian Technological University (M.V. Lomonosov Institute of Fine Chemical Technologies)
Russian Federation

Student of the Chair of Chemistry and Technology of Basic Organic Synthesis

86, Vernadskogo pr., Moscow 119571, Russia



References

1. Lebedev N.N. Chemistry and technology of basic organic and petrochemical synthesis. Мoscow: Khimiya Publ., 1988. 592 р. (in Russ.)

2. Zhukov V.I., Val’kovich G.V., Gershberg M.I. Methods of producing esters and/or their mixtures. Applicant and copyright holder «Stavropolpolymer»: Patent 2127722 RU. – No. 95122059/04, filled 12/26/1995. (in Russ.)

3. Misyukov N.V., Bzhitskiy V.A., Anan’in A.A. Method for the preparation of isoamyl alcohol (variants). Applicant and copyright holder «Nitrometan»: Patent 2196763 RU. – No. 2001113421/04, filled 05/21/2001. (in Russ.)

4. Glukhareva M.I., Nikopaeva N.N., Chachshin A.M., Antonova T.Yu.; Method for the preparation of acetates of monohydric aliphatic alcohols. Applicant and copyright holder «Central Research and Design Institute of the Forestry Industry»: Patent 1744941 RU. – No. 4822074/04, filled 05/03/1990. (in Russ.)

5. Pizzio L., Vazquez P., Caceres C. Tungstophosphoric and molibdophosphoric acids supported on zirconia as esterification catalysts. Catal. Lett. 2001; 77(4): 233-239.

6. Pizzio L.R., Blanco M.N. Isoamyl acetate production catalyzed by H3PW12O40 on their partially substituted Cs or K salts. Appl. Catal. A: General. 2003; 255: 265-277.

7. Romero M.D., Calvo L., Alba C., Habulin M. Enzymatic synthesis of isoamyl acetate with immobilized Candida antarctica lipase in supercritical carbon dioxide. J. Supercrit. Fluids. 2005; 33: 77-84.

8. Zhuchkov V.I., Nazanskiy S.L., Krupinova O.N., Frolkova A.K. Vapour–liquid equilibrium in systems with isobutyl acetate, acetic acid and methyl ethyl ketone. Tonkie khimicheskie tekhnologii (Fine Chemical Technologies). 2016; 11(2): 38-45. (in Russ.)

9. Ogorodnikov S.K., Lesteva T.M., Kogan V.B. Azeotropic Mixtures: St. Petersburg: Khimiya Publ., 1971. 848 р. (in Russ.)

10. Lyudmirskaya G.S., Barsukova T.A., Bogomolniy A.M. Vapor–liquid equilibrium. Handbook. St. Petersburg: Khimiya Publ., 1987. 336 р. (in Russ.)

11. Nagiev M.F. Theoretical foundations of recycling processes in chemistry. Moscow: USSR Academy of Sciences Publ., 1962. 362 p. (in Russ.)

12. Duev S.I. Theory of recycling system reactor – separating unit: D.Sc. (Eng.) Thesis. Мoscow, 1993. 396 p. (in Russ.)

13. Solokhin A.V., Nazanskiy S.L., Timofeev V.S. Feasibility of using infinity separating ability assumption for steady state analysis of recycling systems. Teoreticheskiye osnovy khimicheskoy tekhnologii (Theoretical Foundations of Chemical Technology). 2009; 43(1): 163-172. (in Russ.)

14. Nazansky S.L., Solokhin A.V., Istomina O.Yu. Basic mathematical model of reactor – separation unit system. Khimicheskaya tekhnologiya (Chemical Technology). 2011; 12(7): 437-443. (in Russ.)

15. Solokhin A.V., Nazanskiy S.L., Kiyko A.V. Design and rating calculation of recycled system. Vestnik MITHT (Fine Chem. Technol.). 2013; 8(3): 70-75. (in Russ.)

16. Teo H.T.R., Saha B. Heterogeneous catalysed esterification of acetic acid with isoamyl alcohol: Kinetic studies. J. Catal. 2004; 228: 174-182.


For citation:


Nazanskiy S.L., Glukhova M.S. THE DEVELOPMENT OF A BASIC PROCESS SCHEME FOR THE PREPARATION OF ISOAMYL ACETATE. Fine Chemical Technologies. 2018;13(6):79-88. (In Russ.) https://doi.org/10.32362/2410-6593-2018-13-6-79-88

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