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Questions on selectivity of homo- and crossaldol condensation of lower aldehydes at presence of different salts of amines.

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Abstract

Reactions of homo- and crossaldol condensation of formaldehyde and acetaldehyde were studied at presence of primary, secondary and tertiary amine salt of linear structure in N,N-dimethylacetamide, water and toluene. It was found that in all solvents conversion of reagent is increased with increase of bacity of amine, but selectivity on cross-reaction became lower because of formation side products of acetaldehyde homo-condensation. The conversion of acetaldehyde is also increased with increase of solvent polarity.

About the Authors

L. V. Dashko
M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571
Russian Federation


V. V. Medvedev
M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571
Russian Federation


D. V. Dmitriev
M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571
Russian Federation


V. R. Flid
M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571


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For citation:


Dashko L.V., Medvedev V.V., Dmitriev D.V., Flid V.R. Questions on selectivity of homo- and crossaldol condensation of lower aldehydes at presence of different salts of amines. Fine Chemical Technologies. 2008;3(4):23-31. (In Russ.)

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