Preview

Fine Chemical Technologies

Advanced search

Synthesis of photoaffine arylazide semax derivative

Full Text:

Abstract

The photoaffine arylazide semax derivative has been synthesized using paminobenzoic acid and semax as starting compounds

About the Authors

K. V. Martynova
M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571
Russian Federation


Yu. G. Kirillova
M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571
Russian Federation


I. U. Nagaev
Институт молекулярной генетики РАН
Russian Federation


V. P. Shevchenko
Институт молекулярной генетики РАН
Russian Federation


S. I. Shram
Институт молекулярной генетики РАН
Russian Federation


V. I. Shvets
M.V. Lomonosov Moscow State University of Fine Chemical Technologies, 86, Vernadskogo pr., Moscow 119571
Russian Federation


References

1. Ноотропные эффекты нового аналога фрагмента АКТГ(5–10)-гексапептида АКТГ (5–7) PGP / Н. Ю. Глазова [и др.] // Доклады Академии Наук. – 1999. – Т. 367, № 1. – C. 137-140.

2. Исследование механизмов нейропротективного действия семакса в период острого ишемического удара / Н. Ф. Мясоедов [и др.] // Журн. неврологии и психиатрии. – 1999. – № 5. – С. 15-19.

3. Synthetic ACTH analogue Semax displays nootropic-like activity in humans / A. Ya. Caplan [et al.] // Neuroscience Res. Comm. – 1996. – Vol. 19, № 2. – P. 115-123.

4. Влияние гептапептида семакса на энцефалограмму человека / М. В. Королева [и др.] // Бюлл. эксперим. биологии и медицины. – 1996. – Т. 122, № 11. – C. 527-529.

5. Hatanaka, Y. Photoaffinity labeling in drug discovery and developments: chemical gateway for entering proteomic frontier / Y. Hatanaka, Y. Sadakane // Curr. Topics in Med. Chem. – 2002. – Vol. 2. – P. 271-288.

6. Bayley, H. Photoaffinity labeling / H. Bayley, J.R. Knowles // Methods in Enzymology. – 1977. – Vol. 46. – P. 69-115.

7. Han, S.-Y. Recent development of peptide coupling reagents in organic synthesis / S.-Y. Han, Y.-A. Kim // Tetrahedron. – 2004. – Vol. 60. – P. 2447-2467.

8. Toward the development of radiolabeled fluorophenyl azide-based photolabeling reagents: synthesis and photolysis of iodinated 4-azidoperfluorobenzoates and 4-azido-3,5,6- trifluorobenzoates / S. X. Cai [et al] // J. Org. Chem. – 1992. – Vol. 57. – P. 1299-1304.

9. Photoaffinity labeling of insulin receptor proteins of liver plasma membrane preparations / C. C. Yip [et al]. // Biochemistry. – 1980. – Vol. 19, № 1. – P. 72-76.

10. Photoaffinity labeling of acyl-coenzyme A:glycine N-acyltransferase with p-azidobenzoylcoenzyme A / E. P. Lau [et al] // Biochemistry. – 1977. – Vol. 16, № 12. – P. 2581-2585.


For citation:


Martynova K.V., Kirillova Yu.G., Nagaev I.U., Shevchenko V.P., Shram S.I., Shvets V.I. Synthesis of photoaffine arylazide semax derivative. Fine Chemical Technologies. 2007;2(4):78-82. (In Russ.)

Views: 73


ISSN 2410-6593 (Print)
ISSN 2686-7575 (Online)