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Specifics of cross-aldol condensation of acetaldehyde with formaldehyde in presence of aminoacids and their derivatives

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Abstract

Reaction of cross-aldol condensation of acetaldehyde with formaldehyde at presence of aminoacids and their ether- and benzoil-derivatives were studied in pyridine, N, N-dymethylacetamide, water and toluene. It was shown that aminoacids are capable to catalyse cross- and homocondensation of acetaldehyde. The yield of acrolein in presence of aminoacids is much lower than with use of its derivatives. The selectivity of cross-condensation is dependent from acid-base properties of catalyst and the reaction media. It is found that the main contribute to catalysis of cross-condensation is introduced by amino-group of aminoacid and it basic properties determine the yield of acrolein

About the Authors

L. V. Dashko
МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86
Russian Federation


D. V. Dmitriev
МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86
Russian Federation


V. R. Flid
МИТХТ им. М.В. Ломоносова, 119571, Москва, пр-т Вернадского, д. 86
Russian Federation


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For citation:


Dashko L.V., Dmitriev D.V., Flid V.R. Specifics of cross-aldol condensation of acetaldehyde with formaldehyde in presence of aminoacids and their derivatives. Fine Chemical Technologies. 2009;4(4):49-54. (In Russ.)

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