Стабильность 3', 5'-o-(тетраизопропилдисилоксан-1,3-диил)нуклеозидов в присутствии кислот Льюиса.

Триметилсилилтрифторметансульфонат в 1,2-дихлорэтане при 0⁰C эффективно катализирует изомеризацию 3',5'-O-(тетраизопропилдисилоксан-1,3-диил)- (или TIPDS-)нуклеозидов в 2',3'-O-TIPDS-производные с выходами 55–90%. В присутствии тетрахлорида олова и эфирата трехфтористого бора 3',5'-O-TIPDS-нуклеозиды оказались существенно более стабильны.

защитные группы нуклеозидов, изомеризация, 3′,5′-O-(тетраизопропилдисилоксан-1,3-диил)нуклеозиды, триметилсилилтрифторметан-сульфонат.

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