This article describes the development of information systems for modeling a number of polynomial functions based on experimental data, on the basis of which the parameters of thermoelectric coolers are calculated. The input data is entered manually or by uploading files with input data. The calculation is carried out in several stages, including different types of calculations. Some of them are done in parallel and independently of each other. At the first stage, the functions of the measured quantities are calculated by the method of least squares. On their basis the iterative calculation of the main parameters, and also the calculation of a number of additional parameters of the branches are carried out. For convenience in analyzing results, the IS visualizes them in a tabular form and in the form of graphs, giving them in priority of importance for the operator. The results can be exported by copying or automatically in an Excel file.