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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">chemicallytech</journal-id><journal-title-group><journal-title xml:lang="en">Fine Chemical Technologies</journal-title><trans-title-group xml:lang="ru"><trans-title>Тонкие химические технологии</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2410-6593</issn><issn pub-type="epub">2686-7575</issn><publisher><publisher-name>MIREA – Russian Technological University (RTU MIREA).</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">chemicallytech-688</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CHEMISTRY AND TECHNOLOGY OF MEDICINAL COMPOUNDS AND BIOLOGICALLY ACTIVE SUBSTANCES</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ХИМИЯ И ТЕХНОЛОГИЯ ЛЕКАРСТВЕННЫХ ПРЕПАРАТОВ И БИОЛОГИЧЕСКИ АКТИВНЫХ СОЕДИНЕНИЙ</subject></subj-group></article-categories><title-group><article-title>Therapeutic role of polyunsaturated fatty acids and of their derivatives in pathophysiological processes</article-title><trans-title-group xml:lang="ru"><trans-title>Терапевтическая роль полиненасыщенных жирных кислот и их производных в патофизиологических процессах</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гроза</surname><given-names>Н. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Groza</surname><given-names>N. V.</given-names></name></name-alternatives><email xlink:type="simple">grozanv@gmail.com</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Голованов</surname><given-names>А. Б.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovanov</surname><given-names>A. B.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Наливайко</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Nalivayko</surname><given-names>E. A.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мягкова</surname><given-names>Г. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Myagkova</surname><given-names>G. I.</given-names></name></name-alternatives><email xlink:type="simple">noemail@neicon.ru</email><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>МИТХТ им. М.В. Ломоносова</institution><country>Russian Federation</country></aff><pub-date pub-type="collection"><year>2012</year></pub-date><pub-date pub-type="epub"><day>28</day><month>10</month><year>2012</year></pub-date><volume>7</volume><issue>5</issue><fpage>3</fpage><lpage>16</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Groza N.V., Golovanov A.B., Nalivayko E.A., Myagkova G.I., 2012</copyright-statement><copyright-year>2012</copyright-year><copyright-holder xml:lang="ru">Гроза Н.В., Голованов А.Б., Наливайко Е.А., Мягкова Г.И.</copyright-holder><copyright-holder xml:lang="en">Groza N.V., Golovanov A.B., Nalivayko E.A., Myagkova G.I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://www.finechem-mirea.ru/jour/article/view/688">https://www.finechem-mirea.ru/jour/article/view/688</self-uri><abstract><p>This review presents literature data on studies of the therapeutic role of natural polyunsaturated fatty acids and their derivatives in the processes of inflammation, cancer, and immune response.</p></abstract><trans-abstract xml:lang="ru"><p>В настоящем обзоре представлены литературные данные, посвященные исследованиям тера-певтической роли природных полиненасыщенных жирных кислот и их производных в процессах воспаления, опухолеобразования, иммунных реакциях. </p></trans-abstract><kwd-group xml:lang="ru"><kwd>полиненасыщенные жирные кислоты</kwd><kwd>эйкозаноиды</kwd><kwd>цитотоксичность</kwd><kwd>иммуно-подавляющее действие</kwd><kwd>polyunsaturated fatty acids</kwd><kwd>eicosanoids</kwd><kwd>cytotoxicity</kwd><kwd>immunosuppressive action</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Calder P.C. 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