chemicallytechFine Chemical TechnologiesТонкие химические технологии2410-65932686-7575MIREA – Russian Technological University (RTU MIREA).10.32362/2410-6593-2023-18-3-254-264chemicallytech-1974Research ArticleANALYTICAL METHODS IN CHEMISTRY AND CHEMICAL TECHNOLOGYАНАЛИТИЧЕСКИЕ МЕТОДЫ В ХИМИИ И ХИМИЧЕСКОЙ ТЕХНОЛОГИИDetermination of chlorine-containing compounds in disinfectants using ion-exchange chromatographyОпределение хлорсодержащих соединений в дезинфицирующих средствах с использованием ионообменной хроматографииhttps://orcid.org/0000-0002-7430-4694ЛапинаЕ. А.LapinaE. A.

Лапина Евгения Андреевна, инженер отдела химических исследований

117246, Москва, Научный проезд, д. 18

ResearcherID AEE-8223-2022

Eugenia A. Lapina, Engineer, Chemical Department

18, Nauchnyi pr., Moscow, 117246

ResearcherID AEE-8223-2022 

zhenya_lapina@mail.ruhttps://orcid.org/0000-0002-3232-9332ЗверевС. А.ZverevS. A.

Зверев Сергей Александрович, младший научный сотрудник отдела химических исследований

117246, Москва, Научный проезд, д. 18

ResearcherID C-1526-2019

Sergei A. Zverev, Junior Researcher, Chemical Department

18, Nauchnyi pr., Moscow, 117246

ResearcherID C-1526-2019 

niid.chemlab@gmail.comhttps://orcid.org/0000-0003-2405-9931АндреевС. В.AndreevS. V.

Андреев Сергей Викторович, к.х.н., и.о. заместителя директора Института дезинфектологии

117246, Москва, Научный проезд, д. 18

Scopus Author ID 57192710116

ResearcherID R-9798-2016

Sergei V. Andreev, Cand. Sci. (Chem.), Deputy Director

18, Nauchnyi pr., Moscow, 117246

Scopus Author ID 57192710116

ResearcherID R-9798-2016 

svandreev.niid@gmail.comhttps://orcid.org/0000-0002-3247-5743СахаровК. А.SakharovK. A.

Сахаров Константин Андреевич, к.х.н., научный сотрудник

639798, Nanyang Avenue, 50

Scopus Author ID 6602616498

ResearcherID A-7428-2016

Konstantin A. Sakharov, Cand. Sci. (Chem.), Researcher

50, Nanyang Avenue, Singapore, 639798

Scopus Author ID 6602616498

ResearcherID A-7428-2016 

konstantin.a.sakharov@gmail.comИнститут дезинфектологии ФБУН ФНЦГ им. Ф.Ф. Эрисмана РоспотребнадзораРоссияF.F. Erisman Federal Scientific Center of Hygiene, Research Institute of Disinfectology, RospotrebnadzorRussian FederationШкола материаловедения и инженерии, Наньянский технологический университетСингапурSchool of Materials Science and Engineering, Nanyang Technological UniversitySingapore202302082023183254264Copyright © Lapina E.A., Zverev S.A., Andreev S.V., Sakharov K.A., 20232023Лапина Е.А., Зверев С.А., Андреев С.В., Сахаров К.А.Lapina E.A., Zverev S.A., Andreev S.V., Sakharov K.A.Данная работа распространяется под лицензией Creative Commons Attribution 4.0.This work is licensed under a Creative Commons Attribution 4.0 License.https://www.finechem-mirea.ru/jour/article/view/1974Objectives

Objectives. To develop a method for the determination of hypochlorite, chloride, chlorite, chlorate, and perchlorate ions in solution; to determine the limits of detection and quantitation for ClO−, Cl−, ClO2−, ClO3−, and ClO4− ions; to evaluate the applicability of the developed method and its suitability for disinfectant analysis.

Methods

Methods. Ionic chromatography using a conductometric detection system in isocratic elution mode.

Results

Results. The method developed for chromatographic determination of chlorine-containing ions can be used to quantify the content of hypochlorite, chloride, chlorite, chlorate, and perchlorate ions. In isocratic elution mode at 7.5 mM NaOH and a flow rate of 0.4 mL/min, the content of chlorine-containing ions can be determined with high sensitivity. The presented method does not require the use of expensive equipment for the ultrasensitive analysis of the studied compounds.

Conclusions

Conclusions. A novel method for the simultaneous determination of hypochlorite, chloride, chlorite, chlorate, and perchlorate ions in case of their combined presence is proposed. The technique can be used to carry out routine control of the content of these disinfectant components during use, increasing their effectiveness at the same time as managing associated toxicological risks.

Цели

Цели. Разработать методику определения гипохлорит-, хлорид-, хлорит-, хлорати перхлорат-ионов при их совместном присутствии в дезинфицирующих средствах. Определить пределы обнаружения и пределы количественного определения ионов ClO−, Cl−, ClO2−, ClO3−, ClO4−. Провести расчеты валидационных параметров разработанной методики, а также оценить ее пригодность для анализа дезинфицирующих средств.

Методы

Методы. Ионообменная хроматография с системой кондуктометрического детектирования в изократическом режиме элюирования.

Результаты

Результаты. Новая методика хроматографического определения хлорсодержащих ионов позволяет количественно оценить содержание гипохлорит-, хлорид-, хлорит-, хлорат- и перхлорат-ионов при их одновременном нахождении в модельном растворе и в дезинфицирующих средствах. Изократический режим элюирования 7.5 мМ NaOH при скорости движения потока 0.4 мл/мин позволяет с высокой чувствительностью определять ионы, содержащие атом хлора. Разработанная методика не требует использования дорогостоящего оборудования, необходимого для сверхчувствительного анализа исследуемых соединений.

Выводы

Выводы. Впервые предложена методика определения гипохлорит-, хлорид-, хлорит-, хлорат- и перхлорат-ионов при совместном присутствии. Ожидается, что разработанная методика позволит проводить рутинный контроль содержания этих компонентов в дезинфицирующих средствах при их практическом использовании, что приведет к повышению эффективности применения дезинфектантов на их основе и снижению возможных токсикологических рисков.

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The authors declare that there are no conflicts of interest present.